|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 133 and 420 of Human PiT2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28184 targets PiT2 in WB applications and shows reactivity with Human samples.
The PA5-28184 immunogen is recombinant fragment corresponding to a region within amino acids 133 and 420 of Human PiT2.
Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amphotropic; Gibbon ape leukemia virus receptor 2; GLVR-2; GLVR2; hPit2; MLVAR; murine leukemia virus; murine leukemia virus, amphotropic, receptor for; murine leukemia virus, amphotropic; receptor; Phosphate transporter 2; PIT-2; pit2; Ram1; receptor for; Sodium-dependent phosphate transporter 2; solute carrier family 20 (phosphate transporter), member 2; Solute carrier family 20 member 2
Gene Aliases: GLVR-2; GLVR2; IBGC1; IBGC3; MLVAR; PIT-2; PIT2; Ram-1; RAM1; SLC20A2
UniProt ID: (Human) Q08357
Entrez Gene ID: (Human) 6575
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.