|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 91 and 290 of Human Pirinin|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29778 targets Pirinin in WB applications and shows reactivity with Human samples.
The PA5-29778 immunogen is recombinant fragment corresponding to a region within amino acids 91 and 290 of Human Pirinin.
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-dioxygenase PIR; Pirin; pirin (iron-binding nuclear protein); probable quercetin 2; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
Gene Aliases: PIR
UniProt ID: (Human) O00625
Entrez Gene ID: (Human) 8544
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