|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 µg/ml|
|Immunoprecipitation (IP)||2 µg|
|Western Blot (WB)||1-3 µg/ml|
|Western Blot (WB)||See 1 publications below|
|Immunofluorescence (IF)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||N-terminus of Human plakophilin-1.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B6P; Band 6 protein; Plakophilin-1
Gene Aliases: B6P; PKP1
UniProt ID: (Human) Q13835
Entrez Gene ID: (Human) 5317
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