|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 316 and 597 of Plasma Kallikrein 1B (Uniprot ID#P03952)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34876 targets Plasma Kallikrein in WB applications and shows reactivity with Human and Mouse samples.
The PA5-34876 immunogen is recombinant fragment corresponding to a region within amino acids 316 and 597 of Plasma Kallikrein 1B (Uniprot ID#P03952).
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: antigen, prostate specific; Fletcher factor; kallikrein 3, plasma; kallikrein B, plasma (Fletcher factor) 1; Kininogenin; KLK3; PKK; Plasma kallikrein; plasma kallikrein heavy chain; plasma kallikrein light chain; Plasma prekallikrein; PPK
Gene Aliases: APS; Kal-3; Kal3; KLK3; KLKB1; Pk; PKK; PKKD; PPK; PSA
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule
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