|ELISA (ELISA)||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Chemical|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Progesterone-11alpha-hemisuccinate conjugated to BSA|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11246 targets Progesterone in ELISA and radioimmunoassay applications and shows reactivity with All samples.
The MA5-11246 immunogen is progesterone-11alpha-hemisuccinate conjugated to BSA.
Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 11-alpha-hydroxyprogesterone; Agolutin; C21H30O2; Crinone; hydroxyprogesterone 11; Hydroxyprogesterone alpha; Luteohormone; OHP; Pregn-4-ene-3,20-dione; Progesterone-11a-hemisuccinate
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