|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||See 2 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified human PSA.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
A suggested positive control is normal prostate or prostate carcinoma.
PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Gamma-seminoprotein; Kallikrein-3; kallikrein-related peptidase 3; P-30 antigen; Prostate Specific Antigen; Prostate-specific antigen; PSA; Semenogelase; Seminin
Gene Aliases: APS; hK3; KLK2A1; KLK3; PSA
UniProt ID: (Human) G3XAE3
Entrez Gene ID: (Human) 354
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule
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