|ELISA (ELISA)||5-10 µg/mL|
|Western Blot (WB)||5 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||50% water with 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-43020 detects Prothrombin in human samples.
MA1-43020 has successfully been used in ELISA, WB applications.
MA1-43020 was derived from human prothrombin.
Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine protease
Gene Aliases: F2; PT; RPRGL2; THPH1
UniProt ID: (Human) P00734
Entrez Gene ID: (Human) 2147
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