|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 244 of Human RCBTB1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30672 targets RCBTB1 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-30672 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 244 of Human RCBTB1.
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; CLLD7; CLLL7; GDP/GTP exchange factor (GEF)-like protein; RCC1 and BTB domain-containing protein 1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1
Gene Aliases: 5430409I18Rik; AW111883; CLLD7; CLLL7; E4.5; GLP; RCBTB1
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