|Western Blot (WB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues A(18) S E L G D P E D P G E E A C(31) of human RFX-B.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-4119 detects RFX-B in human samples.
PA1-4119 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~40 kDa protein representing RFX-B in Raji lymphoblastoid cell line.
The PA1-4119 immunogen is a synthetic peptide corresponding to residues A(18) S E L G D P E D P G E E A C(31) of human RFX-B.
RFX-B is the gene responsible for the bare lymphocyte syndrome (BLS) which is characterized by a lack of MHC class II transcription. Subsequently, there is a lack of B and T cell responses to foreign antigens. RFX-B is a MHC class II transcription factor that is defective in BLS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ankyrin repeat family A protein 1; ankyrin repeat-containing regulatory factor X-associated protein; DNA-binding protein RFXANK; Regulatory factor X subunit B; Regulatory factor X-associated ankyrin-containing protein; RFX-B; RFX-Bdelta4
Gene Aliases: ANKRA1; BLS; F14150_1; RFX-B; RFXANK; RFXB
UniProt ID: (Human) O14593
Entrez Gene ID: (Human) 8625
Molecular Function: transcription factor
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