|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 211 of Human RGS2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28162 targets RGS2 in IF and WB applications and shows reactivity with Human samples.
The PA5-28162 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 211 of Human RGS2.
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 24kD; Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; G0S8; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; RGS2
Gene Aliases: G0S8; GIG31; GOS8; RGS2
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