|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 180 of Human RNF5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31793 targets RNF5 in WB applications and shows reactivity with Human samples.
The PA5-31793 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 180 of Human RNF5.
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase RNF5; HsRma1; Protein G16; Ram1 homolog; RING finger protein 5; ring finger protein 5, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF5; RING5; RMA1
Gene Aliases: G16; NG2; RING5; RMA1; RNF5
UniProt ID: (Human) Q99942
Entrez Gene ID: (Human) 6048
Molecular Function: ubiquitin-protein ligase
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