|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||20 ug/ml|
|Immunohistochemistry (IHC)||5 µg/ml|
|Western Blot (WB)||1-2 ug/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid peptide near the carboxy terminus of human RSRC1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is HepG2 cell lysate.
PA5-20899 can be used with blocking peptide PEP-1013.
The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: arginine/serine-rich coiled coil 1; arginine/serine-rich coiled coil protein 1; arginine/serine-rich coiled-coil 1; Arginine/serine-rich coiled-coil protein 1; BM-011, SFRS21, SRrp53; Serine/Arginine-related protein 53; splicing factor, arginine/serine-rich 21; SRrp53
Gene Aliases: 1200013F24Rik; BM-011; RGD1304968; RSRC1; SFRS21; SRRP53
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