|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 721 and 784 of Human Rabenosyn 5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28637 targets Rabenosyn 5 in WB applications and shows reactivity with Human samples.
The PA5-28637 immunogen is synthetic peptide corresponding to a region within amino acids 721 and 784 of Human Rabenosyn 5.
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; FYVE-finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; Rabenosyn-5; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20
Gene Aliases: Rabenosyn-5; RBSN; ZFYVE20
UniProt ID: (Human) Q9H1K0
Entrez Gene ID: (Human) 64145
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