|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
|Western Blot (WB)||Assay Dependent|
|Immunohistochemistry (IHC)||See 3 publications below|
|Tested Species reactivity||Human, Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Microsomal fraction of human renal cortical tissue homogenate|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13362 targets Renal Cell Carcinoma Marker in IHC (P) and WB applications and shows reactivity with Human and Rat samples.
The MA5-13362 immunogen is microsomal fraction of human renal cortical tissue homogenate.
In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Of other normal tissues examined, the gp200 is also localized along the luminal surfaces of breast lobules and ducts, the luminal surface of the epididymal tubular epithelium, within the cytoplasm of parathyroid parenchymal cells, and focally within the colloid of thyroid follicles. Thirty-one other normal tissues do not express similar or cross-reacting antigens. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type lectin domain family 13 member B; carbonate dehydratase IX; carbonic anhydrase 9; carbonic dehydratase; lymphocyte antigen 75; membrane antigen MN; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Gene Aliases: CD205; CLEC13B; DEC-205; GP200-MR6; LY-75; RGD1565962
Molecular Function: receptor
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