|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay dependent|
|Immunohistochemistry (IHC)||See 2 publications below|
|Tested Species reactivity||Goat, Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human plasma RBP.|
|Contains||0.05% sodium azide|
|Storage conditions||4° C|
MA1-35782 only detects methylated RBP. In order to detect RBP, a methylation step of the antigen must be applied.
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cellular retinol binding protein 1; Cellular retinol-binding protein; Cellular retinol-binding protein I; CRBP; CRBP-I; mCRBPI; Retinol-binding protein 1; retinol-binding protein 1, cellular
Gene Aliases: CRABP-I; CRBP; CRBP1; CRBPI; Rbp-1; RBP1; RBPC
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.