|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Plant|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Natural RCA60, full length.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-91115 detects Ricinus communis agglutinin 60 from various samples.
MA1-91115 has been successfully used in Western blot applications.
The MA1-91115 immunogen is: Natural RCA60, full length.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Ricinus communis agglutinin 60 is a heterodimeric glycoprotein consisting of an A chain (RTA, ricin toxin A chain) disulphide-linked to a B chain (RTB, ricin toxin B chain). RTA is an N glycosidase, responsible for ricin cytotoxicity, that depurinates adenine residue 4324 of the 28S rRNA, thus inactivating protein synthesis. Since its endocytotic properties are very limited, RTA alone shows a very low level of cytotoxicity. RTB is a galactose specific lectin containing three galactose-binding sites. Mutation or deletion of any one of these sites reduces the ability of ricin to penetrate into the cell.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ricinus communis agglutinin 60
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