|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant fragment contains a sequence corresponding to a region within amino acids 122 and 451 of SAMHD1|
|Storage buffer||PBS, pH 7|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA5-17280 targets SAMHD1 in IHC (P) and WB applications and shows reactivity with Human samples.
The MA5-17280 immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 122 and 451 of SAMHD1.
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHBL2; DCIP; Dendritic cell-derived IFNG-induced protein; Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; HDDC1; Monocyte protein 5; MOP-5; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; SBBI88
Gene Aliases: CHBL2; DCIP; HDDC1; MOP-5; MOP5; SAMHD1; SBBI88
UniProt ID: (Human) Q9Y3Z3
Entrez Gene ID: (Human) 25939
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