|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 13 amino acid peptide from near the center of human SAPAP4.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is SK-N-SH cell lysate.
PA5-20558 can be used with blocking peptide PEP-0678.
SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAP-4; DAP4, DLP4, RP5-977B1.6, SAPAP4; discs large homolog associated protein 4; discs, large (Drosophila) homolog-associated protein 4; disks large associated protein 4; Disks large-associated protein 4; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4; SAPAP-4
Gene Aliases: DAP-4; DAP4; DLGAP4; DLP4; KIAA0964; SAPAP-4; SAPAP4
UniProt ID: (Human) Q9Y2H0
Entrez Gene ID: (Human) 22839
Molecular Function: transmembrane receptor regulatory/adaptor protein
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