|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 901 and 963 of Human SART3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28625 targets SART3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28625 immunogen is synthetic peptide corresponding to a region within amino acids 901 and 963 of Human SART3.
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DSAP1; HIV-1 Tat-interacting protein of 110kDa; hSART-3; p110 nuclear RNA-binding protein; p110(nrb); RP11-13G14; SART-3; squamous cell carcinoma antigen recognized by T cells 3; Squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; TIP110
Gene Aliases: DSAP1; KIAA0156; P100; p110; p110(nrb); RP11-13G14; SART3; TIP110
UniProt ID: (Human) Q15020
Entrez Gene ID: (Human) 9733
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