|Immunohistochemistry (Paraffin) (IHC (P))||3 µg/ml|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||0.1-0.3 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KERQERKQRLQEN) corresponding to the internal amino acids of SECISBP2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence , a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686C09169; OTTHUMP00000064929; OTTHUMP00000064930; OTTHUMP00000064931; OTTHUMP00000064932; RP11-89K14.1; SBP2; SECIS binding protein 2; SECIS-binding protein 2; SECISBP2; selenocysteine insertion sequence binding protein 2; Selenocysteine insertion sequence-binding protein 2
Gene Aliases: SBP2; SECISBP2
UniProt ID: (Human) Q96T21
Entrez Gene ID: (Human) 79048
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