|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 438 and 660 of Human SCMH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30454 targets SCMH1 in WB applications and shows reactivity with Human and mouse samples.
The PA5-30454 immunogen is recombinant fragment corresponding to a region within amino acids 438 and 660 of Human SCMH1.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Polycomb protein SCMH1; scmh1; Scml3; sex comb on midleg 1; Sex comb on midleg homolog 1; sex comb on midleg-like 1; sex comb on midleg-like 3
Gene Aliases: AI315320; AI851618; SCMH1; Scml1; Scml3
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.