|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse, Pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to an C-terminal region of the human SDHA protein (within residues 500-664).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol, 0.1% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
The target sequence has 94% sequence homology with rat and 93% sequence homology with porcine.
SDHA is an important component in the citric acid cycle and respiratory chain. SDHA converts succinate to fumarate, transfers electrons in the respiratory chain, and ultimately transfers electrons to ubiquinone. SDHA is localized within the mitochondrial inner membrane. Mutations in the gene have been associated with Leigh syndrome and Huntington's disease. However, SDHA also appears to have tumor suppressor effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CMD1GG; Flavoprotein subunit of complex II; Fp; mitochondrial; PGL5; SDH1; SDH2; SDHF; succinate dehydrogenase [ubiquinone] flavoprotein subunit; Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex flavoprotein subunit; succinate dehydrogenase complex subunit A, flavoprotein (Fp); succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Gene Aliases: 1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; CMD1GG; FP; PGL5; SDH1; SDH2; SDHA; SDHF
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