|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Hamster, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 109-135 amino acids from the central region of human SDR|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Caveolae-associated protein 2; Cavin-2; CAVIN2; phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS-p68; SDPR; SDR; Serum deprivation-response protein
Gene Aliases: cavin-2; CAVIN2; PS-p68; SDPR; SDR
UniProt ID: (Human) O95810
Entrez Gene ID: (Human) 8436
Molecular Function: transcription factor
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