|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length human SELENBP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 44 and 53 kDa.
Purity is >95% by SDS-PAGE.
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 56 a selenium binding protein; 56 kDa selenium-binding protein; epididymis secretory sperm binding protein Li 134P; hSBP; Lp 56; Lp56; Lpsb; SBP 1; SBP56; Selen bp2; SELENBP 1; Selenbp 2; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium binding protein2; Selenium-binding protein 1; selenium-binding protein 2; SELNBP1; SP 56; SP56
Gene Aliases: HEL-S-134P; hSBP; Lp56; LPSB; SBP; SBP56; SELENBP1; Selenbp2; SP56
Molecular Function: defense/immunity protein
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