|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human SEMA6A|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse based on sequence homology.
SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HT018; SEMA; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; Sema VIA; SEMA6A-1; SEMA6A1; semaphorin 6A-1; Semaphorin VIA; Semaphorin-6A; Semaphorin-6A-1; SEMAQ; VIA
Gene Aliases: HT018; KIAA1368; SEMA; SEMA6A; SEMA6A1; SEMAQ; VIA
UniProt ID: (Human) Q9H2E6
Entrez Gene ID: (Human) 57556
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