|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DNNKNKGQLTKSP) corresponding to the internal amino acids of 39326|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, equine, mouse, porcine and rat based on sequence homology.
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC10; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 cell division cycle 10 homolog; CDC10 protein homolog; CDC3; cell division cycle 10; Nbla02942; SEPT7; SEPT7A; septin 7; septin 7 variant 4; Septin-7
Gene Aliases: CDC10; CDC3; NBLA02942; SEPT7; SEPT7A
UniProt ID: (Human) Q16181
Entrez Gene ID: (Human) 989
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