|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human SERTAD1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28460 targets SERTAD1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28460 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 44 of Human SERTAD1.
Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; SEI-1; SEI1; SERTA domain-containing protein 1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP-Br1
Gene Aliases: SEI1; SERTAD1; TRIP-Br1
UniProt ID: (Human) Q9UHV2
Entrez Gene ID: (Human) 29950
Molecular Function: transcription factor
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