|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KNHECPTFQSVFK) corresponding to the C-terminus amino acids of SFRP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine and mouse based on sequence homology.
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: frizzled-related protein; FRP; FRP-1; FRP1; FrzA; SARP-2; SARP2; Secreted apoptosis-related protein 2; Secreted frizzled-related protein 1; sFRP-1; SFRP1
Gene Aliases: FRP; FRP-1; FRP1; FrzA; SARP2; SFRP1
UniProt ID: (Human) Q8N474
Entrez Gene ID: (Human) 6422
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