|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with non-human primate and rat based on sequence homology.
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. SGMS2 is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. This protein is required for cell growth.
Protein Aliases: Phosphatidylcholine:ceramide cholinephosphotransferase 2; SM synthase; SMS2; Sphingomyelin synthase 2
Gene Aliases: 4933405A16Rik; 5133401H06Rik; AI854299; SGMS2; SMS2