|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 218-260 of human Lad|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 52 kDa.
Purity is >95% by SDS-PAGE.
Lad (TSAD, TSAd, F2771, SH2D2A, SH2 domain protein 2A) is a 52 kDa cytoplasmic adapter protein that undergoes tyrosine-phosphorylation and influences T cell activation. Lad (SH2D2A) mRNA is present in peripheral blood leukocytes, thymus and spleen, and accumulates in the cytoplasm during T cell activation. The Lad gene maps to chromosome 1q21 in a region where alterations are characteristic to lymphomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SH2 domain containing adapter protein; SH2 domain containing protein 2A; SH2 domain protein 2A; SH2 domain-containing adapter protein; SH2 domain-containing protein 2A; SH22A; Sh2d2a; T cell specific adapter protein; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T cell-specific adapter protein; T lymphocyte specific adaptor protein; TSAd; VEGF receptor associated protein; VEGF receptor-associated protein; VRAP
Gene Aliases: F2771; SCAP; SH2D2A; TSAD; VRAP
UniProt ID: (Human) Q9NP31
Entrez Gene ID: (Human) 9047
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