|Immunofluorescence (IF)||20 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||16 amino acid peptide near the center of human SHBG|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A recommended positive control is human liver tissue lysate.
At least three isoforms of SHBG are known to exist; this antibody will detect all three isoforms.
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABP; androgen binding protein; SBP; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene); Sex hormone-binding globulin; Sex steroid-binding protein; SHBG; TEBG; Testis-specific androgen-binding protein; testosterone-binding beta-globulin; Testosterone-estradiol-binding globulin; Testosterone-estrogen-binding globulin
Gene Aliases: ABP; Abpa; SBP; SHBG; TEBG
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