|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 8 and 223 of Human SIGMAR1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30372 targets SIGMAR1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30372 immunogen is recombinant fragment corresponding to a region within amino acids 8 and 223 of Human SIGMAR1.
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Aging-associated gene 8 protein; ALS16; hSigmaR1; OPRS1; SIG-1R; Sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; sigma1R; SR-BP; SR-BP1; SR31747 binding protein 1; SR31747-binding protein; SRBP
Gene Aliases: AAG8; ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SIGMAR1; SR-BP; SR-BP1; SRBP
UniProt ID: (Human) Q99720
Entrez Gene ID: (Human) 10280
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