|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 324 of Human SKAP55|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28596 targets SKAP55 in IF and WB applications and shows reactivity with Human samples.
The PA5-28596 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 324 of Human SKAP55.
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory sperm binding protein Li 81p; pp55; SCAP1; SKAP-55; SKAP55; src family associated phosphoprotein 1; Src family-associated phosphoprotein 1; Src kinase-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa
Gene Aliases: HEL-S-81p; SCAP1; SKAP1; SKAP55
UniProt ID: (Human) Q86WV1
Entrez Gene ID: (Human) 8631
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