|Western Blot (WB)||1/500 - 1/2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of SKP2 (aa1-130) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-15470 targets SKP2 in WB applications and shows reactivity with Human samples.
The MA5-15470 immunogen is purified recombinant fragment of SKP2 (aa1-130) expressed in E. Coli.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs predominantly in S phase and interacts with S-phase kinase-associated protein 1 . In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates 2 transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDK2/cyclin A-associated protein p45; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; FBL1; FBXL1; FLB1; MGC1366; p45skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); SKP2
Gene Aliases: FBL1; FBXL1; FLB1; p45; SKP2
UniProt ID: (Human) Q13309
Entrez Gene ID: (Human) 6502
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