|Immunocytochemistry (ICC)||5 ug/ml|
|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (LHQGERETWGK) corresponding to the internal amino acids of SLC6A4|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse based on sequence homology.
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HTT; 5-HTTLPR; 5-hydroxytryptamine (serotonin) transporter; 5-hydroxytryptamine transporter; 5HT transporter; 5HTT; HGNC:11050; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163633; serotonin transporter; serotonin transporter 1; SERT; SLC6A4; Sodium-dependent serotonin transporter; solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; Solute carrier family 6 member 4; solute carrier family 6, member 4
Gene Aliases: 5-HTT; 5-HTTLPR; 5HTT; hSERT; HTT; OCD1; SERT; SERT1; SLC6A4
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