|Immunohistochemistry (IHC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1-5 µg/ml|
|Western Blot (WB)||1-5 µg/ml|
|Tested Species reactivity||Bovine, Chicken, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Rat SNAP25 and mouse NS1 Cells.|
|Contains||0.08% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
A suggested positive control for this product is cerebellum tissue lysate.
SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer and quote;s Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; SNAP25; snp25; SUP; Super protein; synaptosomal associated protein-25; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
Gene Aliases: bA416N4.2; Bdr; BOS_12772; CMS18; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; sp; SUP
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