|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Synaptobrevin 1 (aa 1-118) and Synaptobrevin 2(aa 33-96).|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17610 targets SNAP-25 in ELISA, FACS, and WB applications and shows reactivity with Human samples.
The MA5-17610 immunogen is human Synaptobrevin 1 (aa 1-118) and Synaptobrevin 2(aa 33-96).
Synaptic vesicle membrane docking and fusion is mediated by SNAREs located on the vesicle membrane and the target membrane . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: resistance to inhibitors of cholinesterase 4 homolog; SNAP; SNAP-25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
Gene Aliases: bA416N4.2; CMS18; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP25; SUP
UniProt ID: (Human) P60880
Entrez Gene ID: (Human) 6616
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