|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues Q(139) E D Q F D L T V G I T D P E K I(155) of human SNX1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-836 detects SNX1 in human and mouse samples. It is recommended for use with recombinant protein.
PA1-836 has been successfully used in Western blot and ICC/IF procedures. By Western blot, this antibody detects a ~60 kDa protein representing SNX1in human samples.
The PA1-836 immunogen is a synthetic peptide corresponding to residues Q(139) E D Q F D L T V G I T D P E K I(155) of human SNX1. This peptide (Cat. # PEP-286) is available for use in neutralization and control experiments.
Sorting nexin 1 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: sorting nexin 1A; Sorting nexin-1
Gene Aliases: HsT17379; SNX1; VPS5
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