|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Purified His-tagged SOD protein fragment|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: indophenoloxidase B; manganese-containing superoxide dismutase; mangano-superoxide dismutase; Mn superoxide dismutase; SOD2; Superoxide dismutase [Mn], mitochondrial; Superoxide dismutase [Mn], mitochondrial [Precursor]
Gene Aliases: IPO-B; IPOB; Mn-SOD; MNSOD; MVCD6; SOD2
UniProt ID: (Human) E1P5A9
Entrez Gene ID: (Human) 6648
Molecular Function: oxidoreductase
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