|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Western Blot (WB)||1:50|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with 0.1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
MA1-40247 detects SP-D from rat and human samples.
MA1-40247 has been successfully used in ELISA, Western blot and immunohistochemistry (paraffin) applications.
The MA1-40247 immunogen is rat SP-D.
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collectin-7; CP4; Lung surfactant protein D; PSP-D; pulmonary surfactant apoprotein; pulmonary surfactant protein D; Pulmonary surfactant-associated protein D; SFTPD; surfactant associated protein D; surfactant protein D; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4
Gene Aliases: COLEC7; PSP-D; PSPD; SFTP4; SFTPD; SP-D; SPD
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