|Western Blot (WB)||1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (C terminal).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-30328 detects SP17 from human samples.
PA1-30328 has been successfully used in Western blot applications.
The PA1-30328 immunogen is: Synthetic peptide (C terminal).
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 22; CT22; SP17; SP17-1; Sperm autoantigenic protein 17; Sperm protein 17; Sperm surface protein Sp17
Gene Aliases: CT22; SP17; SP17-1; SPA17
UniProt ID: (Human) Q15506
Entrez Gene ID: (Human) 53340
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