|Western Blot (WB)||1-2 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||18 amino acid peptide near the amino terminus of human SPINSTER|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A recommended positive control is human placenta tissue lysate.
At least four isoforms of SPINSTER are known to exist. This antibody is not expected to cross-react with other members of the spinster family of proteins.
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HSpin1; LAT; nrs; PP2030; PP20300; Protein spinster homolog 1; SPIN1; SPINL; spinster homolog 1; Spinster-like protein 1; SPNS sphingolipid transporter 1 (putative)
Gene Aliases: HSpin1; LAT; nrs; PP2030; PP20300; SPIN1; SPINL; SPNS1
UniProt ID: (Human) Q9H2V7
Entrez Gene ID: (Human) 83985
Molecular Function: transporter
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.