|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IMP-2; IMP2; Intramembrane protease 2; Presenilin homologous protein 1; Presenilin-like protein 4; PSH1; PSL4; Signal peptide peptidase-like 3; SPP-like 3; SPP-like 3 protein; SPPL3
Gene Aliases: IMP2; MDHV1887; PRO4332; PSH1; PSL4; SPPL3
UniProt ID: (Human) Q8TCT6
Entrez Gene ID: (Human) 121665
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