|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 302 of Human STAMBP|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29187 targets STAMBP in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-29187 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 302 of Human STAMBP.
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AMSH; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase; STAM-binding protein; testicular secretory protein Li 54
Gene Aliases: 5330424L14Rik; 5730422L11Rik; AMSH; AW107289; MICCAP; mKIAA4198; STAMBP
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