|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 226-253 amino acids from the central region of human STEA2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IPCA1; Metalloreductase STEAP2; PCANAP1; prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane Protein of Prostate 1; STAMP1; STEAP family member 2, metalloreductase; STMP
Gene Aliases: 4921538B17Rik; AI930049; AW045895; IPCA-1; IPCA1; PCANAP1; PUMPCn; STAMP1; STEAP2; STMP; UNQ6507/PRO23203
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