|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human STK11 (LKB1)|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with chicken, mouse and rat based on sequence homology.
STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Liver kinase B1; LKB1; PJS; polarization-related protein LKB1; Renal carcinoma antigen NY-REN-19; Serine/threonine-protein kinase 11; Serine/threonine-protein kinase LKB1; Serine/threonine-protein kinase STK11; STK11
Gene Aliases: hLKB1; LKB1; PJS; STK11
UniProt ID: (Human) Q15831
Entrez Gene ID: (Human) 6794
Molecular Function: non-receptor serine/threonine protein kinase
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