|Immunoprecipitation (IP)||Assay Dependent|
|Immunoprecipitation (IP)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||2-248 of 462 of SUV420H2 Protein.|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Histone-lysine N-methyltransferase KMT5C; Histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; Lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; Suppressor of variegation 4-20 homolog 2; Suv4-20h2; SUV420H2
Gene Aliases: KMT5C; PP7130; SUV420H2
UniProt ID: (Human) Q86Y97
Entrez Gene ID: (Human) 84787
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.