|Immunofluorescence (IF)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Virus|
|Published species reactivity||Virus|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||SV40 transformed mouse line B4|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
This antibody reacts with native and denatured large T-antigen. It does not react with the small T-antigen of SV40 or the large T-antigen of BKV, human papovavirus.
The simian virus 40 large T antigen plays important role in SV40 transfection and transformation of the cells. It binds to Rb and p53 suppressor proteins leading to the inactivation of suppressor pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Simian vacuolating virus 40; Simian virus 40
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