|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 852-880 amino acids from the C-terminal region of human SYNE3|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KASH domain-containing protein 3; KASH3; Nesprin-3; NET53; Nuclear envelope spectrin repeat protein 3; spectrin repeat containing, nuclear envelope family member 3; SYNE3
Gene Aliases: C14orf139; C14orf49; LINC00341; Nesp3; nesprin-3; NET53; SYNE3
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.