|Flow Cytometry (Flow)||1:100 -1:1000|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:100|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
We recommend using fixation with either 2% paraformaldehyde or ethanol for optimal results.
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD169; dJ1009E24.1; SER; Sheep erythrocyte receptor; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; Sialoadhesin; SIGLEC-1; SN
Gene Aliases: Cd169; Sa; Siglec-1; Siglec1; Sn
UniProt ID: (Mouse) Q62230
Entrez Gene ID: (Mouse) 20612
Molecular Function: cell adhesion molecule cytokine receptor defense/immunity protein immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule membrane-bound signaling molecule myelin protein receptor signaling molecule structural protein
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